Abstract. According to the IPCC Fourth Assessment, the temperature and evapotranspiration will increase in the future. As a sensitive region to climate change, hydrological process in the middle reaches of the Yellow River will be significantly affected by climate change. In this study, water resources change in the future for a typical basin there: Lushi basin is assessed using the Soil and Water Assessment Tool (SWAT) hydrological model. Downscaled ensemble output from sixteen General Circulation Models (GCMs) for the A1B emission scenario in the 2050s was input to SWAT as the regional climate change scenario. The prediction shows that ET of this basin increases in winter and spring, and decreases in summer and autumn, and the streamflow increases throughout the year. The increased streamflow will probably improve the water demand guarantee and be conducive to crop growth in winter and spring, and may improve the flood risk in summer.