The effects of land subsidence could be devastating on heavily settled coastal plains. In a scenario of sea-level rise, high costs are expected to protect coastal cities and touristic hotspots and to keep drained reclaimed lands. In this work, we calculated subsidence rates (SR) in the Po coastal plain, over the last 5.6 and 120 thousand years, providing information about land movements before human intervention became the main driver of subsidence, through water and gas withdrawal.